Semaglutide is a GLP-1 weight loss medication. GLP-1s are different from older classes of prescription weight loss medications (like phentermine) because they work on key underlying metabolic pathways to support sustained weight loss. GLP-1s work on the same receptors as your naturally occurring GLP-1 hormones. They help reduce inflammation, regulate digestion, improve metabolic function, and decrease your risk for cardiovascular disease—ultimately helping you live a longer and healthier life.
Simple & Sustainable
Metabolic Weightloss
Medical Weightloss with Semaglutide
Traditional diets don’t work because sustainable weight loss comes from improving your metabolic health—LeanMD helps you do just that.
How GLP-1 Weightloss Medications
Help Thousands Lose Weight

REDUCES
INFLAMMATION
GLP-1s are clinically proven to reduce inflammation markers, leading to decreased inflammatory response and oxidative stress. CRP (C-reactive protein), a general inflammatory marker, is one marker we may follow during your Metabolic Reset.

IMPROVES
METABOLIC FUNCTION
GLP-1s regulate blood sugar levels by increasing insulin and decreasing glucagon—only when blood sugar levels are high. GLP-1s also improve whole-body energy metabolism by increasing insulin sensitivity of muscle cells and regulating fat cell development.

REGULATES
DIGESTION
GLP-1s slow how quickly food moves from the stomach to the intestines. This helps you feel full for longer by regulating sugar absorption in the intestine.
Frequently Asked Questions
About GLP-1 Weight Loss Medication
GLP-1s are FDA-approved, clinically-tested, stimulant-free, and non-habit forming. Not only are they safe, but research shows that they are the most effective medications for sustainable weight loss, especially when combined with lifestyle changes. GLP-1s are generally very well tolerated, with limited side effects. Many individuals don’t have any side effects at all. However, for those who do, nausea is the most common, and this typically resolves over the first few weeks. In the most recent clinical trials, at the highest dose, less than 5% of people discontinued GLP-1 medications because of side effects. With direct access to your Medical Team for help with titrating and managing side effects through secure messaging, we expect even less difficulty with side effects. Your Medical Team is available throughout the program for any questions about medication side effects or other medical concerns.
Contact Us about Semaglutides
GLP-1 are the safest and most effective long-term option for weight loss. By mimicking the effect of GLP-1 hormones naturally produced in the gut, GLP-1s address your underlying metabolic health. Contact us today to learn if you’re eligible!